Surface Active agent or Surfactants form a unique class of simple chemical compounds that lower the surface tension (or interfacial tension) between two liquids, between a gas and a liquid, or between a liquid and a solid. Surfactants touch our everyday lives in countless ways. They are present in our food, our drinks, and the products that we use to clean ourselves (e.g., soaps, shampoos, toothpaste, shower gel) clean clothes (detergents), cosmetic that we apply (e.g., creams, lotions, gels, perfumes), the medicines that we take (syrups, tablets, injections) just to name the few. Surfactants are usually an organic amphiphilic substances containing hydrophilic, polar or ionic, head group and hydrophobic, non-polar chain.
It is very important societal need to understand the impact of using various surfactant based formulations (personal care and health care) on us or why things or process work the way they do and to understand the applications of these processes. We have developed a profound understanding with tailored approach for utilizing green surfactants in mixtures for various cosmetic product formulations by working in close collaborations with industry on the following aspects:
G Rajput, DL Manyala, N Pandya, V Patel, D Varade, Unusual Stability and Catalytic Activity of Gold Nanoparticles in Polyoxyethylene Cholesteryl Ether, J. Nanoscience and Nanotechnology 20 (4), 2171-2178, 2020.
V Kumar, N Pal, AK Jangir, DL Manyala, D Varade, A Mandal, K Kuperkar, Dynamic interfacial properties and tuning aqueous foamability stabilized by cationic surfactants in terms of their structural hydrophobicity, free drainage and bubble extent, Colloids and Surfaces A: 588, 124362, 2020.
D Varade, S Iki, K Aramaki, Tuning the Viscoelastic Properties of Wormlike Surfactant Micelles by Oil Solubilization, Journal of Nanofluids 8 (2), 379-385, 2019.
M Shah, J Shah, H Arya, A Vyas, A Vijapura, A Gajipara, A Shamal, M Bakshi, P Thakore, R Shah, V Saxena, D Varade, S Singh, Biological Oxidase Enzyme Mimetic Cu-Pt Nanoalloys: A Multifunctional Nanozyme for Colorimetric Detection of Ascorbic Acid and Identification of Mammalian Cells, ChemistrySelect 4 (21), 6537-6546, 2019.
Professor Dharmesh Varade
Mohan Bhadru - Project Fellow in UGC-DAE Project
Dhanalakshmi Manyala - Doctoral Student
Niki Pandya - Doctoral Student
Gajendra Rajput - Doctoral Student
Research at Cloud Computing and Data Analytics Laboratory is dedicated for research advances in the areas of Cloud Computing and Big Data Analytics. The laboratory provides computational and network resources required for
modelling, design, programming, virtualisation, and deployment of innovative software services and products in these areas. Research students and scholars use these lab resources to address advanced research challenges in these domains. Current research projects are Developing Big Data Analytics, Architecture, Developing Data Content Standards, and ICT Interventions to Improve the Performance of Canal Irrigation Sector.
S. Madria, P. Fournier-Viger, S. Chaudhary, and P. K. Reddy (Eds.), Big Data Analytics 7th International Conference BDA2019 Proceedings, Lecture Notes in Computer Science book series (LNCS, volume 11932) Springer, 2019
Ratnik Gandhi, Mehul S Raval, "Learning Algorithms over Cloud", Nature-Inspired Computation in Data Mining and Machine Learning (NICDL2018), Editors: Xin-She Yang, Springer Cham, pp: 23-46, Sept. 2019. ISBN: 978-3-030-28552-4, DOI https://-doi.org/101007/978-3-030-28553-1_2
Mehul S Raval, Ratnik Gandhi, Sanjay Chaudhary, "Insider Threat Detection: Machine Learning Way", Eds. Mauro Conti, Gaurav Somani, and Radha Poovendran, Versatile Cybersecurity, Springer Book series: Advances in Information Security, pp. 19 ¬53, October 2018, ISBN: 978-3-319-97642-6, DOI: 10:1007/978-3-319-97643-3
S. Chaudhary, G. Somani, and R. Buyya (Eds.), Research Advances in Cloud Computing, Springer Nature, ISBN 978-981-10-5025-1, 2017
S. Chaudhary and V. Kumar, Service Oriented Architecture and Spatial Data Integration for Agro Advisory Systems, in Book: Geospatial Infrastructure, Applications and Technologies: India Case Studies, N. L. Sarda • P. S. Acharya • S. Sen (Eds.), Springer
Nature Singapore Pte Ltd., pp. 185-199, ISBN 978-981-13-2329-4, 2018
M. P. Patel and S. Chaudhary, Edge Computing: A Review on Computation Offloading and Light Weight Virtualization for loT Framework, International Journal of Fog Computing (I JFC), IGI Global, 2020, DOI: 10.4018/1 JFC.2020010104
P. Shah, S. Chaudhary, Big Data Analytics Framework for Spatial Data. In: Mondal A., Gupta H., Srivastava J., Reddy P., Somayajulu D. (eds) Big Data Analytics. BDA 2018. Lecture Notes in Computer Science, vol 11297, Springer, pp 250-265, Cham, 2018
Aditya Parikh, Mehul S Raval, Chandrasinh Parmar, Sanjay Chaudhary, "Disease Detection and Severity Estimation in Cotton Plant from Unconstrained Images", Special Session on Data Science for Agricultural Decision Support Systems at 3rd IEEE International Conference on Data Science and Advanced Analytics (DSAA 2016), 17 - 19th Oct. 2016, Montreal, Canada.
A. Nathani, S. Chaudhary, and G. Somani, Policy Based Resource Allocation in IaaS Cloud, Future Generation Computer Systems Journal, Volume 28, Issue 1, January 2012, Pages 94-103 DOI: http://dx.doi.org/10.1016/j.future.2011.05.016
Professor Sanjay Chaudhary
Professor Mehul Raval
Hiren Tyagi, Doctoral Student
Deepak Hiremath, Doctoral Student
The Communication and Signal Processing Laboratory mainly focuses on the design, analysis, and testing of xG and beyond wireless communication systems along with the research from signal processing perspective. Signal processing being a broad term includes Image processing, Computer vision, speech and Natural language processing. One of the major research areas of labortory is computer vision and image processing (CVIP). Image Processing and Computer vision helps to observe the world using spatial signals or spatio-temporal signals. The goal is to draw inference about the observed world. The modern CVIP relies on Artificial Intelligence and uses deep learning, classical machine learning, statistical analysis and inference, and optimisation techniques.
Rupal Agravat, Mehul S Racal, "3D Semantic Segmentation of Brain Tumor for Overall Survival Prediction", A. Crimi and S. Bakes (Eds.): International MICCAI Brainlesion Workshop: BrainLes 2020, Springer LNCS.
Hiren Caliyawala, Mehul S Ravel, Shivansh Dave, 'Visual Appearance Based Person Retrieval in Unconstrained Environment Videos-, Image and Vision Computing, VoL 92, Dec.2019.
Dhaval K. Patel, Brijesh Soni, and Miguel L6pez-Benitez, "Improved likelihood ratio statistic-based cooperative spectrum sensing for cognitive radio", IET Communications, VoL14, no:11, pp. 1675-1686, January 2020.
Dhaval K. Patel, Brijesh Soni, and Miguel LOpez-Benftez, "On the estimation of primary user activity statistics for long and short time scale models in cognitive radio", Springer Wireless Networks, pp 1-13, August 2019
Bansi Gajera, Dhaval K. Patel, Brijesh Soni, and Miguel Lopez-Benitez, "Performance Evaluation of Improved Energy Detection Under Signal and Noise Uncertainties in Cognitive Radio Networks", Proceedings of the 3rd International Conference on Signals and Systems 2019 (ICSigSys 2019), Bandung-Indonesia, pp 1-6, July 16-18, 2019
Shivam Ravel, Dhaval K. Patel, Miguel Lopez-Benitez, "Performance Analysis of Improved Energy Detection in Full Duplex Non-Time-Slotted Cognitive Radio", Proceedings of the IEEE 12th International Conference on Advanced Networks and Telecommunications Systems Indore, India, pp. 1-6, December 16 -19, 2018
Professor Mehul Raval
Professor Dhaval Patel
Rupal Agravat, Doctoral Student
Hiren Galiyawala, Doctoral Student
Sagar Kavaiya, Doctoral Student
Maitrik Shah, Doctoral Student
Srishti Sharma, Doctoral Student
Brijesh Soni, Doctoral Student
The Computational Fluid Dynamics (CFD) Lab, deals with understanding of different aspects from small to large scale. On a smaller scale, CFD can be utilized for understanding the transport phenomena like heat and mass transfer from drops/bubbles. Further, it can be utilized to model large scale industrial equipment's like power plant or process plant like heat exchangers, crystallizers, liquid-liquid extractors etc. The aim is to understand the underlying fluid dynamics and transport phenomena and recommend design optimization of these equipment's which would lead to improvement in efficiencies of the equipment's. Currently, simulations are carried out to understand two phase flows in microchannels and related miniaturized equipments as well as single phase flows in pilot scale equipments like stirred vessels, steam distributors, solar chimneys etc.
A.A. Ganguli, A.G. Patel, N.K. Maheshwari, A.B. Pandit, 2008. Theoretical modeling of condensation of steam outside different vertical geometries (tube, flat plates) in the presence of non-condensable gases like air and helium. Nuclear Engineering and Design, 238, 2328-2340.
A.A. Ganguli, M.J.Sathe, A.B. Pandit, J.B. Joshi, P. Vijayan, 2010. Hydrodynamics and heat transfer characteristics of passive decay heat removal: CFD simulations and experimental measurements. Chemical Engineering Science. 65, 3457 — 3473
M.S. Gandhi, A.A. Ganguli, J.B. Joshi, 2011. CFD simulations of steam distribution in header-tube assemblies. Chemical Engineering Research and Design, 90, 487 - 506
A.A. Ganguli, E.K. Kenig, 2011. A CFD based approach to interfacial mass transfer at free gas-liquid interfaces. Chemical Engineering Science. 66, 3301 — 3308
R.T. Eiswirth, H.-J. Bart, A. A. Ganguli, E.Y. Kenig 2012, Experimental and numerical investigation of binary coalescence: Liquid bridge building and internal flow fields, Phys. Fluids 24, 062108.
Chinmay V. Rane, Arijit A. Ganguli, Ekambara Kalekudithi, Raosaheb N. Patil, Jyeshtharaj B. Joshi and Doraiswami Ramkrishna, 2014. CFD simulation and comparison of industrial crystallizers, Canadian Journal of Chemical Engineering, 92, 2138 - 2156
Punjabi S. B., Barve D. N., Ghorui S., Das A.K., Joshi N.K., Kothari D.C., Ganguli A.A., Sahasrabudhe S.N., and Joshi J.B., Computational Fluid Dynamics (CFD) Simulations and Experimental Measurements in an Inductively-Coupled Plasma Generator Operating at Atmospheric Pressure: Performance Analysis and Parametric Study, Processes, 7, 133, 1-30
Professor Arijit Ganguli
The primary focus of the energy conversion research is to design and develop thermal energy systems which converts solar energy into power, heat and/or cooling effectively. Solar refrigeration system, Solar PV/thermal system, Solar energy based space heating system are taken up for the research works.
The refrigeration system is primarily driven by electric power generated through conventional energy resources and it is reported that 15% of the world's electricity is consumed by refrigeration processes. In efforts to conserve the valuable conventional energy resources, development of efficient adsorption refrigeration system driven by waste heat/solar thermal energy is considered for the research work.
Today, thermal energy storage is one of the important topics of the research work as it stores energy when there is surplus energy and can be utilised when there is need. Phase change materials are such materials and are utilized widely for the space heating and cooling applications. The focus here is to develop the best design of phase change material storage systems on heat transfer point of view for the space heating and cooling applications.
Nitin. D. Banker, Devandra Dandotfya, Sal Yams' Middy Morthala, Mahern Caddam and Srictrar KatiLetl, Evaluation of Minimum, Maximum and Optimum Source Temperattre for Solar Powered Adsorption Refrigeration System, Arabian formal for Science and Engineering, 2020, online available. irttpsu- dotorg/10:1007/s13369-020-0485S-0
Ralcesh Singhai, Harender Sinhmar and Banker ND, Effect of Aspect Ratioof Heliostat on Cost of Energy from Solar Power Tower Plants, Arabian Jour attar Science and Engineering, 2020, 45, pp. 877-890.
Reath Singhal, Patin D. Banker, Harender, Sitar, Sart:11;1101in and Shilchar Kulstwesth, Effect of Aspect Patio of Heliostat; on Optical Efficiency of Sdr Tower Power Plant- An Experimental Analysis, Energy Source; Part A: Recovery, Utilization, and Erwironmental Effects, 2020, Online available_101080/15567036.2020.1751745
Ashwath Vaictiyanathan and Banker ND, Theoretical and Experimental Modeling of Phase Change Material based Space Heating wing Solar Energy, intemationallournalaAir-tondrtionlig and Refrigeration, 2020,28 (2), pp. 2050016-1 to 2050016-12.
Shildiar Ager,val, Vansh Mend, Mtn D Banker, Pratilsha Blawat, Experimental Studies on Space Heating Laing Plane Change Material (PCM), Energy storage, 2020, Special issue. Doi: httpsii-dol.orgrI01002/est2.209
Nitin. D. Banker, Devendra Dandottya, Energy Efficiency improvement of a Refrigerator integrated with Phase Change Material based Condenser, ASME J. Energy know: TechnoL, 2020, Accepted. dot httprlidol.org/10..T115/1.4048871
Professor Nitin Banker
Sasmita Patnaik, Doctoral Student
Energy Storage Materials research area includes with the nano and micro material preparation for energy application; solid state materials for hydrogen storage; sand to silicon nano sheets for Li ion batteries and Process Integration. This research area covers the synthesis and characterisation of novel materials for hydrogen storage and lithium ion batteries applications. The goal of this area is conversion of waste (laboratory glass and sand) to favourable materials is of great significance for sustainable strategies. The various strategies and experimental setups have been developed to work on these areas. The main focus of this area is to use low cost approach to synthesise the cheap, nontoxic and highly efficient material for batteries.
Disha Ravipatia, Shweta Singh, Sridhar Dalai, "Effect of Heat Treatment Temperature and Time on Preparation of Porous Walled Hollow Glass Microspheres (PWHGMs)", Journal of Physics: Conf. Series, 1455 (2020) 012013.
Shweta Singh, Disha Ravipati, Darshan Dedaniya, Jay Fadadu, Jay Kumar Patel, Vikas Patel, Sridhar Dalai, "To Study the Effect of Particle Size of Sand and Magnesium Powder on conversion of Sand to Nano-silicon", Journal of Physics: Conf. Series, 1455 (2020) 012014.
Sridhar Dalai, S.Vijayalakshmi, and Pratibha Sharma, "Investigating the effect of cobalt loading on thermal conductivity and hydrogen storage capacity of hollow glass microspheres (HGMs)", in Materials Today Proceedings, 4, 11608-11616 (2017).
Sridhar Dalai, S.Vijayalakshmi, Pragya Shrivastava, Santosh Param Sivam and Pratibha Sharma, "Fabrication of zinc loaded hollow glass microspheres (HGMs) for hydrogen storage" International Journal of Energy Research (I JER), 39, 717-726 (2015).
Sridhar Dalai, Vijayalakshmi Savithri, Ko Yeon Choo, Pratibha Sharma, "Magnesium and Iron loaded hollow glass microspheres for hydrogen storage (HGMs)" International Journal of
Hydrogen Energy (I JHE), 39,16451-16458(2014).
Sridhar Dalai, S.Vijayalakshmi, Pragya Shrivastava, Santosh Param Sivam, Pratibha Sharma, "Effect of Co loading on the hydrogen storage characteristics of hollow glass microspheres (HGMs)", International Journal of Hydrogen Energy (I JHE), 39,3304-3312(2014).
Professor Sridhar Dalai
Moulie Ghosh, Doctoral Student
Clean and environmental friendly energy is the most important need of the 21st century. It is well known that the use of fossil fuels causes problems connected with source availability as well as with environmental compatibility. Hydrogen is going to be an important part of future energy systems and therefore, electrocatalysts that will evolve hydrogen with the lowest possible energy consumption will be very important. Electrocatalysis of water can be the best way to bridge the global energy supply between the present era of fossil fuels and the future era based on hydrogen economy. Water splitting, however, is controlled by difficult oxygen evolution reaction (0ER) step because it involves 4 electrons and 4 protons transfer. If an efficient catalyst for OER could be developed, hydrogen can be produced efficiently by combining the catalyst with a solar device.
In this way, oxygen and hydrogen can be generated without hampering the environment.
In this context, we have focused on designing more advanced cobalt based metal oxides and substituting them with transition metals. Cobalt oxide based materials have been chosen because they are economical and have shown promising activity towards OER recently.
Subramanian Nellaiappan , Navneet Jhariya, Silvia Irusta, Aditi Singhal*, "Platinum substituted Cobalt(II, III) Oxide: Interplay of tetrahedral Co (II) sites towards electrochemical oxygen evolution activity", Electrochimica Acta, 365, 137234, 2021 (IF -6.2)
Vishal Vats and Aditi Singhal*, "Effect of Ru substitution in La0.85Sr015Co03 towards oxygen evolution reaction: Activity of ionic Ru", Electroanalysis, 32, 1-10, 2020 (IE - 2.54)
Divya Vyas, Aditi Singhal and Sudhanshu Sharma, "One step rapid synthesis of Mesoporous high surface area Sn1-xSbxO2: Electrochemical and scanning tunneling spectroscopic studies", J. Phys. Chem. Solids, 123, 355-363, 2018 (IF- 2.21)
Aditi Singhal*, Anuj Bisth and Silvia Irusta "Enhanced oxygen evolution activity of Co3-xNixO4 compared to Co3O4 by low Ni doping", J. Electroanal. Chem.,823 ,482-491, 2018 (IF -3.2)
Aditi Singhal*, Bhanu P Gangwar, Gayathry J M, "CTAB modified large surface area Nanoporous Geopolymer with high adsorption capacity for copper ion removal", Applied Clay Science, 150, 106-114, 2017 (IF -3:1)
Aditi Singhal*, Anuj Bisht, Amit Kumar, Sudhanshu Sharma*, "One pot, rapid synthesis of Co3O4 by solution combustion method and its electrochemical properties in different electrolytes", J. Electroanalytical Chemistry, 776, 152-161, 2016 (IF -3.2)
Professor Aditi Singhal
Sourav Mal, Project Fellow (DST-SERB)
Ionic Liquids Applications Laboratory is intended to explore the applications of green solvents in separation and reaction. Ionic liquids (ILs) are tunable solvents having low vapour pressure. The ILs are widely used in the separation of alcohols from aqueous solution. It is widely used for the separation of aliphatic and aromatic compounds. The equilibrium data generation for the screening of solvent is the main task in this laboratory. Also, the density functional theory and molecular simulation have been applied to study the thermodynamics properties, molecular interaction and rate kinetics. It helps in deciding the solvent or catalyst for separation or reaction, respectively prior to the experiment.
Ronak Patel, Dharamashi Rabari, Sanjay Patel, "Feasibility analysis of Ca-looping sorption enhanced steam reforming of bio-butanol for SOFC application: comparative study with steam and auto-thermal reforming", Energy Sources, Part A: Recovery, Utilization, and Environmental Effects, 2020, https://-dolorg/101080/15567036.20201765900
"Phase Equilibria in Ionic Liquid Facilitated Liquid-liquid Extractions", Tamal Banerjee, Dharamashi Rabari, Debashish Kundu, Anand Bharti, CRC Press, March 2017, ISBN 9781498769488 - CAT# K29303.
Anand Patel, Dharamashi Rabari, "Optimiza¬tion of Multistage Extractor for the separation of butanol from Aqueous Solution using Ionic Liquids", 8th International Congress on Ionic Liquids, May 13-17, 2019, Beijing, China.
Hirai Bhatt, Dharamashi Rabari, "The optimiza¬tion of catalyst cluster: a quantum calcula¬tion", CHEMCON-2018, December 27-30, 2018, NIT Jalandhar, Punjab, India.
Professor Dharamashi Rabari
Mahula Santra, Doctoral Student
The Machine Intelligence, Computing and xG Networks (MIcXN) is a dedicated research lab that spans several aspects of Artificial Intelligence, Computational Biology, Futuristic xG wireless networks, and emerging bio-inspired nano-networks; with the aim to address the cutting-edge research problems through an interdisciplinary approach and providing theoretical/experimental breakthroughs as potential solutions. In particular, the key research focus includes the application of Artificial Intelligence in xG and beyond wireless networks for smart sensing framework, EDGE computing in Non-orthogonal Multiple access (NOMA) technique, Dynamic spectrum resource allocation for Intelligent Transportation System, Biology and Social Computing, and disease monitoring using molecular communications through Internet of Bio-Nano Things (IoBNT). Moreover, this lab is also equipped with high-end computing facility resource like GPU. The lab is also involved in bio engineering research cluster mainly focused on research problems like molecular communications and Covid 19 predictions. The research investigates proactive diseases mechanism with the help of internet of bio Nano things, the bio markers identifications for subject target disease and develop mathematical modelling and Al algorithms for advanced disease detection. The research also investigates prediction of Covid 19 based on weather conditions such as temperature, moisture and relative humidity etc.
Sagar Kavaiya, Dhaval K. Patel, Y. L. Guan, S. Sun, Y. C. Chang and J. M. Lim, "Physical Layer Security in Cognitive Vehicular Networks", IEEE Transactions on Communications, November 2020 (Accepted for publication)
Shweta Thakur, Dhaval K Patel, Brijesh Soni, Mehul Raval, Sanjay Chaudhary, "Prediction for the Second Wave of COVID-19 in India" is accepted for publication in The Eighth International Conference on Big Data Analytics (BDA), December 15 - 18, 2020 at Ashoka University, Sonipat, India. (Accepted for publication)
Dhaval K. Patel, Brijesh Soni, and Miguel Lopez-Benitez, "Artificial Neural Network Design for Improved Spectrum Sensing in Cognitive Radio", Springer Wireless Networks, pp 6155-6174, July 2020
Brijesh Soni, Dhaval K. Patel and M. Lopez-Benitez, "Long Short-Term Memory Based Spectrum Sensing Scheme for Cognitive Radio Using Primary Activity Statistics," in IEEE Access, vol. 8, pp. 97437-97451, 2020.
Sagar Kavaiya, Dhaval K. Patel, Y. L. Guan, S. Sun, Y. C. Chang and J. M. Lim, "On the Energy Detection Performance of Multiantenna Correlated Receiver for Vehicular Communication using MGF Approach", IET Communications, Vol. 14, no. 12, pp. 1858 —1868, April 2020.
0. H. Toma, M. Lopez-Benitez, Dhaval K. Patel and K. Umebayashi, "Estimation of Primary Channel Activity Statistics in Cognitive Radio Based on Imperfect Spectrum Sensing," in IEEE Transactions on Communications, vol. 68, no. 4, pp. 2016-2031, April 2020
0. H. Toma, M. Lopez-Benitez and Dhaval K. Patel, "Analysis of the Sample Size Required for an Accurate Estimation of PrimaryChannel Activity Statistics under Imperfect Spectrum Sensing," IEEE 31st Annual International Symposium on Personal, Indoor and Mobile Radio Communications, London, United Kingdom, 2020, pp. 1-6.
Sagar Kavaiya, Dhaval K. Patel, Y. L. Guan, S. Sun, Y. C. Chang and J. M. Lim, "On the Physical Layer Security over a-n-k-1.1 Fading for Relay based Vehicular Networks", Proceedings of the 10th IEEE International Conference on Signal Processing and Communications (SPCOM-2020), IISc — Banglore, pp. 1-6, July 20-23, 2020
0. H. Toma, M. LOpez-Benitez, Dhaval K. Patel and K. Umebayashi, "Reconstruction Algorithm for Primary Channel Statistics Estimation Under Imperfect Spectrum Sensing", Proceedings of the 18th IEEE Wireless Communications and Networking Conference, pp 1-6, May 25-28, 2020
0. H. Toma, M. LOpez-Benitez, Dhaval K. Patel and K. Umebayashi, "Reconstruction Algorithm for Primary Channel Statistics Estimation Under Imperfect Spectrum Sensing", Proceedings of the 18th IEEE Wireless Communications and Networking Conference, pp 7-12, May 25-28, 2020
M. Lopez-Benitez, 0. H. Toma, Dhaval K. Patel and K. Umebayashi, "Sample Size Analysis of Energy Detection under Fading Channels", Proceedings of the 6th IEEE WCNC International Workshop on Smart spectrum pp 1-6, May 25-28, 2020.
M. Lopez-Benitez, 0. H. Toma, Dhaval K. Patel, "Mathematical Models for the Accuracy of the Estimated Distribution of Primary Activity Times in DSA", Proceedings of the 6th IEEE WCNC International Workshop on Smart spectrum, pp 7-12, May 25-28, 2020.
Professor Dhaval Patel
Professor Akhand Rai
Professor Subhash Rajpurohit
Brijesh Soni, Doctoral Student
Sagar Kavaiya, Doctoral Student
As a broadly-trained materials researcher from development to device fabrication, I am well-suited to understand the correlation between materials and its performance at the system level. At MSCL, we are studying the development of material, fundamental properties and evaluate device performance. Overall idea is to integrate three strands of research, development, and understanding of new material in bulk as well as thin film, make a device and check the reliability at small and large scale, within the context of sustainability. In addition to it, we are also interested exploring the phase transition materials for energy application, in particular, multiferroic alloy that goes through first order transition. This encompasses a broad class of systems in several fields, from physics to materials science to mechanics to mechanical engineering, understanding of thermodynamics, microstructures, and hysteresis.
Deepak Verma, et.al., Role of defect density on the electronic transport and current-voltage characteristics of the hole transporter free perovskite solar cell, Materials
Today: Proceedings, https://doi.org/101016/j.mat-
Zeel Purohit, Deepak Verma, and Brijesh Tripathi, Electro-analytical investigation of potential induced degradation in mc-silicon solar cells: case of sodium ion induced inductive loop, Phys. Chem. Chem. Phys. 20, (2018) 19168.
Deepak Verma, Ole-Morten and T.O. Saetre A report on efficient hybrid solar cells, 26th European Photovoltaic solar energy conference, held at Humberg , Germany, ISBN:3-936338-27-2, (2011) pp. 580 - 586, Paper D01:10.4229/26thEUPVSEC2011-1DV.3.34
Deepak Verma, A.Ranga Rao and V. Dutta Surfactant free CdTe Nanoparticles mixed MEH-PPV hybrid solar cell deposited using spin coating technique, Solar Energy Materials and Solar Cells 93, (2009) 1482.
Deepak Verma and V. Dutta Role of novel microstructure of polyaniline-CSA thin film in ammonia sensing at room temperature, Sensors and Actuator: Chemical B 134 (2008) 373.
Deepak Verma and V.Dutta, Bi-nanoparticles mixed Polyaniline hybrid thin films for solar cell application, journal of Applied Physics 105 (2009) 034904
Professor Deepak Verma
We are interested in the design, analysis and implementation of networked systems. Our current focus is on the development of network architectures and protocols with provable performance guarantees. Although the Internet had been a tremendous success, it is designed to give only "best effort" service, meaning that no performance guarantees are given. This results in unbounded worst case behavior of key performance metrics, such as, latency, reliability and jitter. Deterministic networks refer to those networks that provide bounded worst case performance guarantees. A wide range of emerging applications in Cyber-Physical Systems and Internet of Things domains
depend on availability of deterministic networks. A deterministic Internet will usher in yet another technological revolution. Our work uses mathematical analysis and simulation as well as implementation and validation on hardware platforms. We also seek synthesis of results from other disciplines to solve Computer Science problems.
K. S. Prabh and T. F. Abdelzaher, "Energy conserving data cache placement in sensor networks," ACM Transactions on Sensor Networks, vol. 1, no. 2, 178-203, 2005.
K. S. Prabh and T. F. Abdelzaher, "On scheduling and real-time capacity of hexagonal wireless sensor networks," Proceedings of the 19th Euromicro Conference on Real-Time Systems (ECRTS), 136-145, 2007.
K. S. Prabh and J. Hauer, "Opportunistic packet scheduling in body area networks," Proceedings of the 8th European Conference on Wireless Sensor Networks (EWSN), 114-129, 2011.
K. S. Prabh, F. Royo, S. Tennina and T. Olivares, "A MAC protocol for reliable communication in low power body area networks," Journal of Systems Architecture, vol. 66-67, 1-13, 2016.
K. S. Prabh, "A maximum dispersion approach for rate feasibility problems in SINR model," Proceedings of the 15th International Symposium on Modeling and Optimization in Mobile, Ad Hoc and Wireless Networks (WiOpt), 338-345, 2017.
Professor Shashi Prabh
Ozone based Technology Laboratory is intended to work on the technology development of water treatment and air pollution treatment using ozone. The focus is on the integration of ozone and other advanced oxidation process and catalysis for the removal of recalcitrant micropollutants from wastewater. These integration methods have been also utilized for the oxidative removal studies of air pollutants such as 502, NOX, and VOCs. Multiple reactors and experimental setups have been developed in our laboratory to work on these areas. The focus is to develop the ozone-based technology for the removal of these gaseous pollutants which would be low cost, highly efficient, and easy to install at the user's site. Other related area of research is to synthesize heterogeneous catalysts to facilitate the ozone-based process and reduce the ozone slip and usage.
Khuntia, S., Sinha, M.K., Mohan, G., Evaluation of Reaction Kinetics for Removal of NOx by Ozone and Hydrogen Peroxide, Ind. Eng. Chem. Res. 59, 40, 17806-17814, 2020.
Khuntia, S., Sinha, M.K., Saini, B., Conversion of NO2 through ozonation and peroxone process in gas and aqueous phase: Finding the suitable process through experimental route, Chem. Eng. J. 387,124082, 2020.
Saini, B., Vaghani, D., Khuntia, S., Sinha, M.K., Patel, A., Pindoria, R., A novel stimuli-responsive and fouling resistant PVDF ultrafiltration membrane prepared by using amphiphilic copolymer of
poly(vinylidene fluoride) and Poly( 2 -N-morpholino)ethyl methacrylate, J. Membr. Sci. 603, 118047-118059, 2020.
Saini, B., Khuntia, S., Sinha, M.K., Incorporation of cross-linked poly(AA-co-ACMO) copolymer with pH responsive and hydrophilic properties to polysulfone ultrafiltration membrane for the mitigation of fouling behavior. J. Membr. Sci. 572, 184-197, 2019.
Khuntia, S., Sinha, M.K., Saini, B., An approach to minimize the ozone loss in a series reactor: A case of peroxone process. J. Environ. Chem. Eng. 6, 6916-6922, 2018.
Professor Snigdha Khuntia
Gokuiesh Mohan, Project Assistant
Moulie Ghosh, Doctoral Student
The Cancer Biology lab works on uncovering epigenetic mechanisms of cancer progression and development of non invasive assays for early diagnosis of cancers. Professor Vivek Tanavde is interested in the role of micro RNAs (miRNAs) in cancer progression as well as using miRNAs for early cancer detection. His laboratory is developing innovative liquid biopsy assays for early diagnosis and therapeutic monitoring of oral squamous cell carcinoma patients using salivary exosomes. The laboratory has identified a few miRNAs robustly expressed in oral tumours and are currently validating their utility as biomarkers for prognosis of oral cancer patients. Professor Noopur Thakur's laboratory works on understanding epigenetic mechanisms of cancer. Her laboratory is specifically interested in the crosstalk between TGF-beta signaling and epigenetic modifications in regulating the process of epithelial to mesenchymal transition (EMT) during tumorigenesis.
TN F-alpha regulates alternative splicing of genes participating in pathways of crucial metabolic syndromes; a transcriptome wide study. Louis JM, Vaz C, Balaji A, Tanavde V, TaLukdar I. Cytokine. 2020 Jan;125:154815. doi: 101016/j.cyto.2019.154815. Epub 2019 Aug 30.
Discovering Putative Protein Targets of Small Molecules: A Study of the p53 Activator Nutlin. Nguyen MN, Sen N, Lin M, Joseph TL, Vaz C, Tanavde V, Way L, Hupp T, Verma CS, Madhusudhan MS. J Chem Id Model.
2019 Apr 22;59(4):1529-1546. doi: 10.1021/acs.jcim.8b00762. Epub 2019 Mar 8.
Decreased expression of cell adhesion genes in cancer stem-like cells isolated from primary oral squamous cell carcinomas. Mishra A, Sriram H, Chandarana P, Tanavde V, Kumar RV, Gopinath A, Govindarajan R, Ramaswamy S, Sadasivam S. Tumour Biol. 2018 May; 40 (5): 1010428318780859. doi: 10.1177/ 1010428318780859.
Smad7 Enhances TGF-13-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells. Thakur N, Hamidi A, Song J, Itoh S, Bergh A, Heldin CH, Landstrom M. iScience. 2020 Sep 3;23(9):101470. doi: 10.10164isci.2020101470.
TGF-13 promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85a. Hamidi A, Song J, Thakur N, Itoh S, Marcusson A, Bergh A, Heldin CH, Landstrtini M. Sci Signal. 2017 Jul 410(486):eaa14186. doi: 10.1126/scisignal.aa14186.
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner.Sorrentino A, Thakur N, Grimsby S, Marcusson A, von Bulow V, Schuster N, Zhang S, Heldin CH, Landstrom M. Nat Cell Biol. 2008 Oct;10(10):1199-207. doi: 10.1038/ncb1780. Epub 2008 Aug 31.PMID: 18758450
Professor Vivek Tanavde
Professor Noopur Thakur
Shanaya Patel Bakeri, DBT-Research Associate and former National Post Doctoral Fellow
Shivangi Nautiyal, Doctoral Student and Inspire Fellow
Ankit Naik, Doctoral Student and Inspire Fellow
Dr. Jyoti Tak, DBT-SERB Junior Research Fellow
Nidhi D, Doctoral Student, and CSIR- NET qualified
Stuti Jain, Doctoral Student
Aditi Patel, Doctoral Student
Biology of invasive species: Biological invasions impact and alter an existing ecosystem in different ways, affecting populations, physiological processes and behavioral ecology of native species, and disease dynamics, as well. With regard to this research area, we attempt to explore and understand the following subtopics: a) how does an exotic species impact the biology of native species, b) are there any conservation consequences of invasions, c) can a cutting edge biological tool be developed for improved detection of the invasive species. Currently, we are using Sailfin Catfish (Pterygoplichthys spp), a freshwater fish, and a native from South America as a model system for the study under both laboratory and field conditions.
Role of communication in animal world: Communication is one of the most contentious issues in animal behavior, and the complications arise when animals try to communicate with conspecific individuals within a multispecies assemblage. Animals use multiple modes of communication, namely, olfactory, visual, tactile, and acoustic, and the communication dynamics change under different contexts.
We are using a range of different freshwater fish species, Goldfish, Guppy, Orange Chromide, Tilapia, to understand role of visual and olfactory mode of communication under different social contexts, foraging, mate choice, habitat preference. We attempt to compare and contrast the communication signals between conspecific and hetero-specific assemblages to understand social information transfer and significance of "signature signals" for a particular species.
Conservation physiology of vertebrates: Physiology of vertebrates is intricately related to the environment that they belong to. Animals of the same species may have contrastingly different behavioural patterns, and in turn, physiological mechanisms under varied environmental conditions. With this background, we focus on understanding stress and reproductive physiology of large vertebrates under different ecological conditions, for example, disturbed (anthropogenic disturbances) versus pristine forest patches, captive versus free-ranging conditions, isolated versus continuous habitats, populations having equal versus skewed sex ratio. Currently, we are using 2 species of large vertebrates, the Marsh Crocodile and the Leopard, as model systems for the study. The lab is equipped in assessing hormonal physiology of wild vertebrates through non-invasive sampling, while extracting hormone metabolites from fecal and urine samples. The lab also represents India within the network labs of the International Society of Wildlife Endocrinology, USA.
Peer Reviewed Publications:
Sorensen PW, Rue MC, Leese JM, Ghosal R, Lim H. A Blend of F Prostaglandins Functions as an Attractive Sex Pheromone in Silver Carp. Fishes 4, 27, 2019.
Bajer PG, Ghosal R, Maselko M, Smanski MJ, Lechelt JD, Hansen G, Kornis MS. Biological control of invasive fish and aquatic invertebrates: a brief review with case studies. Management of Biological Invasions, 10, 227-54, 2019.
Ghosal R, Eichmiller, JJ, Witthuhn BA, Sorensen PW. Attracting Common Carp to a bait site with food reveals strong positive relationships between fish density, feeding activity, environmental DNA, and sex pheromone release that could be used in invasive fish management. Ecology and Evolution, 18, 6714-6727, 2018.
Popular Article Publications:
Hussan A, Sundaray JK, Ghosal R and Mallick S. Lovesome chum of the aquarium are wreaking havoc in East Kolkata Wetlands, India. Aquaculture Asia, 24 (July-September), 9-15, 2020.
Mukherjee S, Ghosal R, Datt M and Desai B. Preliminary assessment of use of dorsal scute patterns to identify wild Muggers in human-dominated landscapes of central Gujarat, India. IUCN Crocodile Specialist Group (CSG) newsletter Newsletter, 39 (April-June), 15-18, 2020.
Professor Ratna Ghosal
Nirali Panchal, Project Fellow
Brinky Desai, Doctoral Student
Chena Desai, Doctoral Student
Suman Mallick, Doctoral Student
Research at the Evolutionary Genomics Laboratory addresses two fundamental aspects: Molecular mechanisms in evolution and First-principles prediction of evolutionary traits. We approach these aspects by performing experimental evolution in microorganisms such as E. coli, S. cerevisiae, and Chlorella (algae) in a variety of laboratory environments, and mathematical modeling. The goal is to identify key changes in the genetic program that lead to the organism's adaptation to various stresses and investigate the underlying principles of the emergence of novel phenotypes by experiments and theory. We are also interested in developing methods to infer the evolutionary history of the emergence of new phenotypes from genomic and transcriptomic data. Current research projects in the Evolutionary Genomics Laboratory are in the areas of speciation and hybrid vigor, evolutionary dynamics of the stress response, and evolution of symbiosis and cooperation.
Krishna B. Swamy#, Scott C. Schuyler, Jun-Yi Leu# (2020) Protein Complexes Form a Basis for Complex Hybrid Incompatibility, (In review, Frontiers in Genetics).
Chu CC, Swamy KB, Li H (2020), Tissue-Specific Regulation of Plastid Protein Import via Transit-Peptide Motifs. The Plant Cell 32 (4), 1204-1217, doi: 101105/tpc19.00702
Swamy KB#, Zhou N (2019) Experimental evolution: its principles and applications in developing stress-tolerant yeasts. Applied Microbiology and Biotechnology, 103(5), 2067-2077, 10.1007/s00253-019-09616-2
Zhou N*, Swamy KB*#, Leu JY, McDonald MJ, Galafassi 5, Compango C, Piskur J. (2017) Coevolution with bacteria drives the evolution of aerobic fermentation in Lachancea kluyveri, PLOS ONE .Page no1-19, doi:101371/jour-nal.pone.0173318
Lu YJ, Swamy KB, Leu JY (2016) Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast, PLOS Genetics. Page no 1-26, doi.org/101371/jour-nal.pgen1006409
Professor Krishna. B S Swamy
Pareesha Modi, Project Assistant
Vaidehi Shah, Project Assistant
EEE Lab is interested in understanding responses of organisms to changing environment i.e. warming. Our approach is from 'macrophysiology to molecules'. The focus is on interaction between phenotypic plasticity and adaption, and relationship between underlying physiological and molecular mechanisms. Ecological changes drive evolution which acts on organism's physiology and thereby fitness. The ecological conditions are never stable, and organisms must cope with varying conditions i.e. physiological performance or some form of regulation. We do it by either manipulating organisms or their environments. We also make use of experimental evolution to study how physiological systems function and evolve under defined conditions. The combined approach we follow help us understand ecological patterns and processes, survival in and adaptation to a changing world.
Arya H, Toltesi R, Eng M, Bhati H, Merritt TJS, Rajpurohit S. 2020. Dehydrated Drosophila don't diddle, under review.
Rajpurohit S, Vrkoslav V, Hanus R, Gibbs AG, Cvacka J, Schmidt PS. 2020. Post-eclosion temperature effects on insect cuticular hydrocarbon profiles. Ecology and Evolution, accepted.
Vasquez-Procopio J, Rajpurohit S, Missirlis F. 2020. Cuticle darkening correlates with increased body copper content in Drosophila melanogaster. Biometals dolorg/101007/s10534-020-00245-1.
Durmaz E, Rajpurohit S, Betancourt N, Fabian DK, Kapun M, Schmidt PS, Flatt T. 2019. A clinal polymorphism in the insulin signaling transcription factor foxo contribute to life-history adaptation in Drosophila. Evolution 73:1774-1792.
Professor Subhash Rajpurohit
Harshita Bhati, Doctoral Student
Divita Garg, Doctoral Student
The area of current research is 'Chemical & Molecular Cell Biology of host-pathogen interactions'. The research direction involves understanding genetic, biochemical & metabolic basis underlying the strategies used by fungal pathogens to evade host immunity, and the mechanisms by which plant/animal hosts respond to defend themselves against the microbial attack.
Shah H., Rawat K., Ashar H., Patkar R.N.*, Manjrekar J.*. 2019. Dual role for fungal-specific outer kinetochore proteins during cell cycle and development in Magnaporthe oryzae. Journal of Cell Science. 132: jcs224147 doi: 101242/jcs.224147 (as Co-Corresponding author).
Patkar R.N.* and Naqvi N.I.* 2017. Fungal Manipulation of Hormone-Regulated Plant Defense. PLoS Pathogens. 13(6): e1006334. https://doi.org/101371/journal.ppat.1006334 (as Co-Corresponding author).
Patkar R.N.*, Benke P., Qu Z., Constance C.Y., Fan Y., Swarup S. and Naqvi N.I.* 2015. A Fungal
Monooxygenase-Derived Jasmonate Attenuates Host Innate Immunity. Nature Chemical Biology 11: 733-40. (as Co-Corresponding author).
Professor Rajesh Patkar
Sayali Bakore, Doctoral Student
Abhijit Das, Doctoral Student
V. Anand Parnandi, Doctoral Student
Nentriciencs and Nanoofotedinology: The anticancer drug-mediated cancer treatment is frequently hindered by the drug solubility, bioavaitability, and toxicity profiles, therefore, developing an effective approach for delivering a new drug is as important as Inventing a new drug. Various nanotechnological approaches for effective drug delivery have been developed and some of them have already been successfully commercialized. In this context, we develop approaches to hide therapeutic drugs withal the nano-based drug delivery systems (Ilposomal formulation, polymer-drug conjugate, and drug ft ctionaLized solid nanoparticles) and test them in variety of living cell experimental model systems. We have also developed several drug delivery systems carrying two drugs, a combination of drug and nucleotides, and fluorescence molecules with solid nanopartides.
Next generation enzymes (4anozyrnes): Nancayrnes (nanopartides exhibiting natural enzyme's artalyticfunctlon) haysshown the capabilities to address the limitations of natural enzymes such as low stability, high cost, and stringent storage conditions. The control two-unusual properties of nanornateriaLs offers modulation of intrinsic catalytic properties of these nanozymes as antioxidant or pro-oxidant and offer multifunctional platform with a broad applications from In vitro detection to In vivo real-time monitoring and therapy. We attempt to the systematic design and construction of functionally specific nanozymes, antioxidant (superoxide diunutase and caialase etc.) and pro-oxidant (oxidase aid peroxidase etc), and the exploration of their applications in cell inaging, protection of living cellsfrom oxidative stnns, and cancer cell phenotypkig.
Nanatechnology for "On Rile analysts and Food Forenslcr -On field' / 'point of care' detection systems can accelerate scorning methods that nn help to get confirmed results as soon as possible. Nowadays, we are Living in a system where, we are directly or indirectly exposed to various hazardous materials which can be a threat to human life. In this order, our research group is engaged to design and develop nano-based sensing platforms for "on-spot"/ "point of care" detection system with greater specificitythan existng screening methods. In addition, our research group is also engaged to detect adulterants in our local/packaged/branded food products. Generally, to enhance the texture, taste or stability synthetic dyes, diemkals and other additives are intentionally or wintertionally added into the food products. These rampant irwtancesof adulteration and contamination in esserrtialfoodscan be a potential source of disease infection or toxic poisoning. Our research group is not only focusing in detecting such type of adulterants, but also assessingtheir effect on biomolecules.
Vidhi Jain, Stuti Bhagat, Sanjay Singh. Bovine sewn albumin decorated gold nanodusterr A fluorescence-based nanoprobe for detection of Intracellular hydrogen peroxide. Sensors and Actuators B: Chemica12021;327:128886.
Pratap C Naha, Jessica C Hsu, Johoon Kim, Shay Shah, Mathilde Boothe, Saran Si-Mohamed, Derick N Rosario-Basics, Philippe Douek, Maryam Harathallan, Parise Vain!, Sanjay Singh, Mat A Rosen, Matthew A Morgan, David P Corm ode. Dextran-Coated Cerium Oxide Nanoparticles: A Computed Tomography Contrast Agent for Imaging the Gastrointestinal Tract and Inflammatory Bowel Disease, ACS Nano. 2020:10187-97.
NV Srikenth ValLebanl AJayan Vim, Sanjay Singh, Ajay Karel:oft Tiring the ATP-triggered pro-oxidant activity of Iron oxide-based nanozyme towards an efficient antibacterial grater?. Journal of Colloid and Interface Science. 2020;567:154-64.
juhl Shah, Alok Pandya, Prateek Goyal, Superb K Mlsra, Sanjay Singh. BSA-decorated magnesium nanopartides for scavenging hydrogen peroxide from human hepatic cells. AC Applied Nano Materials. 2020;3(4)3355-70.
Stud Bhagat, SanjaySingh, Co-delivery of AKT3 sIRNA and PTEN Plaunld by Anticaidarrt NanoUposomes for Enhanced Antiprollferation of Prostate
Cancer Cells. ACS Applied ale Materials. 2020;3(7): 3999-4011. (Cover Page Article)
Victor Baldim, Mahe Yadav, Nkolas Dia, Alain Graillot, Cedric Loubit, Sanjay Singh, /gay S Karakoti, Jean-Francols Barret. Polymer-Coated Cerium Oxide Nanoparticks as Osidoreductase-like Catalysts. Acs Applied Materials & Interfaces. 202012(37):42056-66.
K. Koureni, N. Kapeor, A. Badlye, R.K. Shads, *Detection of syntheticfood color Iletanil Yellow' in sweets: a systematic approach', JPC- Journal of Planar Chromatography-Modern TLC, 33,413-418, 2020.
N.V. Vallabani, S. San Gupta, R.K. Shulda, A. Miner, "ZnO NPs Associated Mitochondrial Stress Induced Apoptosis Activation and C2/P-1 Arrest in HaCaT Galls: A Mechanistic Approach', Mutagenesis, 34, 3, 265-277, 2019.
Afiandya, R.K. Shulda, 'New Perspective of Nanotechnology: Role in Preventive Forensic", Egyptian Journal of Forensic Science', 8, 57 1-11, 2018.
H. Dave, N, Bhandari, B. Mod, R.K. Shulda, A. Pandya, "Multifunctional silver-cellulose nanocomposite as a promising plasmatic sensing platform", Journal of Nanosdence and Nanotedinolori, 18, 8, 5461-5469, 2018.
Professor Sanjay Singh
Professor Ritesh Shukla
Juhi Shah, Doctoral Student
Nisha Yadav, Doctoral Student
Stuti Bhagat, Doctoral Student
Vishal Unadkat, Doctoral Student
Harsh Dave, Project Junior Research Fellow
Aishwarya Joshi, Doctoral Student
Nimit Shah, Project Junior Research Fellow
Environmental Nanotechnology, Nano-based drug and gene delivery, Nanoemulsions for food industries, Nanotoxicology, Anti-leishmanial therapeutics, Molecular Parasitology.
Ashutosh Kumar's laboratory focuses on nanomedicines for cancer and arthritis therapy, nanoemulsions for food fortification, environmental nanotechnology and nanotoxicology. It is also involved in understanding the fate of new chemical entities in aquatic ecosystem.
Souvik Sen Gupta is interested in molecular parasitology and anti-leishmanial therapeutics. The goal of his research is to identify novel genes/proteins from the leishmania genome which can serve as potential targets for anti-leishmanial therapeutics with special reference to the DNA repair and cell death pathways in these unicellular protozoan parasites. He is also interested in identifying novel strategies and molecules for effective anti-leishmanial therapeutics.
Kansara K, Kumar A, Karakoti AS (2020) Combination of humic acid and clay reduce the ecotoxic effect of TiO2 NPs: A combined physico-chemical and genetic study using zebrafish embryo. Science of the Total Environment; 698:134133.
Kansara K, Paruthi A, Misra SK, Karakoti AS, Kumar A (2019) Montmorillonite Clay and Humic Acid Modulate the Behavior of Copper Oxide Nanoparticles in Aqueous Environment and Induces Developmental Defects in Zebrafish Embryo. Environmental Pollution; 255(2):113313.
Patel P, Meghani N, Kansara K, Kumar A (2019) Nanotherapeutics for the treatment of cancer and arthritis. Curr Drug Metab.; 20(6):430-445.
Vallabani NVS, Sengupta S, Shukla RK, Kumar A (2019) ZnO nanoparticles-associated mitochondrial
stress-induced apoptosis and G2/M arrest in HaCaT cells: a mechanistic approach. Mutagenesis; 34(3):265-277.
Souvik Sen Gupta
Bhagat 5, Parikh Y, Singh S, Sengupta 5 (2019) A novel nanoliposomal formulation of the FDA approved drug Halofantrine causes cell death of Leishmania donovani promastigotes in vitro. Colloids and Surfaces A: Physicochemical and Engineering Aspects; 582:123852.
Shah A, Sengupta 5 (2019) Anti-leishmanial Nanotherapeutics: A Current Perspective. Curr Drug Metab.; 20(6):473-482.
Das SK, Rehman I, Ghosh A, Sengupta S, Majumdar P, Jana B, Das BB. (2016) Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells. Nucleic Acids Res.; 44(17):8363-8375.
Professor Ashutosh Kumar
Professor Souvik Sen Gupta
Ramesh Chaudhari, Doctoral Student
Abdulkhaik Mansuri, Doctoral Student
Simran Nasra, Doctoral Student
Kikku Sharma, Doctoral Student and CSIR-UGC NET qualified
Anjali Thakkar, Project Junior Research Fellow and CSIR-N ET qualified
The research focus of the laboratory is sensory neurophysiology, with an emphasis on electrosense in weakly electric fish and auditory sense. Within sensory processing, our work is focused on coding, detection, and estimation of behaviourally relevant signals that are either at the limits of sensory threshold (i.e., extremely weak, or faint signals) or corrupted by noise. The processing of near-threshold signals and noisy signals has important survival advantage and has presumably been subjected to strong selective pressure. This may have led to the evolution of an optimal neural code. We have identified one possible code, a spike-timing code, where incoming sensory stimuli are represented with high fidelity (for a fixed energy or metabolic load), while suppressing noise in low-frequency bands relevant for the transmission of behavioural signals. This code results in theoretically optimal stimulus detection and estimation performance. Our laboratory uses in vivo single-neuron electrophysiology and behavioural experiments, mathematical models, and computations to further our understanding of the neural code.
Sidhu RS, Johnson EC, Jones DL, Ratnam R (2020). Adaptation with correlated noise predicts negative interval correlations in neuronal spike trains. (In review, PLoS Computational Biology).
Johnson EC, Jones DL, Ratnam R (2016). A minimum-error, energy-constrained neural code is an instantaneous rate-code. Journal of Computational Neuroscience 40:193-206.
Jones DL, Johnson EC, Ratnam R (2015). A stimulus-dependent spike threshold is an optimal neural coder. Frontiers in Computational Neuroscience. 9:61.
Johnson EC, Jones DL, Ratnam R (2015). Minimum squared-error, energy-constrained encoding by adaptive threshold models of neurons. Proceedings IEEE International Symposium on Information Theory (ISIT 2015), pp 1337-1341.
Professor Rama Ratnam
Sakshi Dokania, Doctoral Student
Alexander Asilador, Doctoral Student