Ramya investigated the abatement of conventional and emerging persistent organic contaminants by an electrochemical advanced oxidation process, namely, electro-peroxone. A novel 3D-Graphene-coated Nickel Foam (Gr-NF) electrode was used to achieve a comprehensive treatment of pharmaceutical compounds and mechanisms behind enhanced reactive oxygen species generation were elucidated. She also designed the first-ever electrically bound biofilm reactor (EBBR) for enhancing biofilm formation. She has studied enhancement of biofilm growth and its application for removing emerging contaminants in water by bio-electrochemical methods. She has also researched treatment of textile dyes and textile wastewater treatment using Fenton and electro-peroxone systems. In another research, she explored hybrid electrochemical advanced oxidation for wastewater treatment in which a novel hybrid bi-functional rotating dual drum electrode system capable of simultaneous photo-electrocatalysis and electro-Fenton processes was developed. An electro-catalyst (Graphene-ferrocene) and photo-catalyst (MoS2 − TiO2) were synthesised for the efficient removal of persistent organic pollutants. This system achieved a complete and rapid removal of ciprofloxacin, an antibiotic drug within a reaction time of 30 minutes.