Research Interests: Signaling, Cancer And Epigenetics.
Dr. Noopur Thakur has joined as an Assistant Professor at Division of Biological and Life Sciences, Ahmedabad University, Gujarat, India in June 2017. She did her M.Sc at the Dept. of Molecular and Human Genetics, Banaras Hindu University, Varanasi and Ph.D in understanding the epigenetic regulation of the imprinted genes with the title " Long range Control of Gene Expression by Imprinted Control Regions During Development and Neoplasia " at the Dept. of Animal Development and Genetics, Uppsala University, Sweden. Following Ph.D, she worked as a postdoctoral fellow ( 2005-2010) at the Ludwig Institute for Cancer Research, Uppsala, Sweden. As a postdoc she worked on the role of TGFbeta signaling in Prostate Cancer. We were the first ones to demonstrate how TGFbeta activates the non-canonical signaling pathway leading to apoptosis ( Nature cell Biology, 2008). Later joined as a Senior Researcher (2010-2015) at the Ludwig Institute for Cancer Research, Uppsala, Sweden. She continued her work on TGFbeta Signaling and its role in Cancer. She had shown in her research how TGFbeta regulates various cellular functions and thus plays an important role in Cancer ( Nature Communication, 2011,Cell Cycle, 2014 and Science Signaling, 2017). Got a well reputed Swedish Cancer Fonden Grant for three years ( 2009-2012).
At Ahmedabad University, Dr. Noopur Thakur is focussed on the role of TGFbeta and other growth factors in maintaining the epigenetic state of the cells and the mechanism how it gets deregulated in the Cancer cells.
Marene Inga-Britt Landström, Yabing Mu, Reshma Sundar, Noopur Thakur, Shyam Kumar Gudey, Maria Ekman, Carl-Henrik, Heldin. Cleavage inhibitors of transforming factor beta type I receptor and uses thereof in cancer therapy. US20140140998, WO2012125623A2, WO2012125623A3.